Caffeine and Sodium vs Dextroamphetamine — Cost, Coverage & Plan Comparison

Pick the drugs you want to compare.

Up to 4 drugsCross-class or same-class

Start with the molecules your plan spends the most on. Most useful comparisons live within the same therapeutic class — switching across classes requires deeper clinical review.

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Drug 2

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Side by side, line by line.

Federal data onlyNo PBM pricing assumed

Compare across

11 dimensions

Central Nervous System Stimulant

Caffeine and Sodium

First FDA approval: 1993-02-01

Central Nervous System Stimulant

Dextroamphetamine

Brand: DEXEDRINE

First FDA approval: 1976-08-02

Lowest NADACAcquisition cost floor across all NDCs

—Per unit

$0.442Per unit

Average NADACAcross all dosage forms and strengths

—

$3.73Up to $16.32

Generic manufacturersActive ANDA holders — FDA Orange Book

00 total ANDAs filed

1134 total ANDAs filed

Annualized Part D spendCY2024 — CMS Part D Spending Dashboard

—Full year

$15.3MFull year

Part D claims (CY24)Total fills, all strengths

—— beneficiaries

145K29K beneficiaries

Avg cost per claimCalculated: total spend ÷ total claims

—Per claim, all NDCs

$105Per claim, all NDCs

Part D plans surveyed2026 plan year — CMS Formulary file

329Across CMS plan year

Prior-authorization frictionPlan-NDC pairs requiring PA

—Zero PA friction

7Minimal friction

Step therapy appliedPlan-NDC pairs requiring step therapy

—None

0None

FDA shortage statusLive cross-reference vs FDA Drug Shortage Database

NoneClear

Generic availableFDA Orange Book

NoBrand-only

Yes11 manufacturers