Calcipotriene, Betamethasone Dipropionate vs Calcipotriene and Betamethasone Dipropionate — Cost, Coverage & Plan Comparison

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Vitamin D Analog

Calcipotriene, Betamethasone Dipropionate

Brand: Calcipotriene and Betamethasone Dipropionate

First FDA approval: 2020-01-30

Vitamin D Analog

Calcipotriene and Betamethasone Dipropionate

Brand: ENSTILAR

First FDA approval: 2008-06-01

Lowest NADACAcquisition cost floor across all NDCs

$1.72Per unit

$0.886Per unit

Average NADACAcross all dosage forms and strengths

$2.28Up to $2.84

$6.54Up to $21.80

Generic manufacturersActive ANDA holders — FDA Orange Book

00 total ANDAs filed

33 total ANDAs filed

Annualized Part D spendCY2024 — CMS Part D Spending Dashboard

—Full year

Part D claims (CY24)Total fills, all strengths

—— beneficiaries

Avg cost per claimCalculated: total spend ÷ total claims

—Per claim, all NDCs

Part D plans surveyed2026 plan year — CMS Formulary file

329Across CMS plan year

Prior-authorization frictionPlan-NDC pairs requiring PA

3Minimal friction

60Minimal friction

Step therapy appliedPlan-NDC pairs requiring step therapy

1Limited friction

FDA shortage statusLive cross-reference vs FDA Drug Shortage Database

NoneClear

Generic availableFDA Orange Book

NoBrand-only

Yes3 manufacturers