Chlordiazepoxide vs Clonazepam — Cost, Coverage & Plan Comparison

Pick the drugs you want to compare.

Up to 4 drugsCross-class or same-class

Start with the molecules your plan spends the most on. Most useful comparisons live within the same therapeutic class — switching across classes requires deeper clinical review.

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Side by side, line by line.

Federal data onlyNo PBM pricing assumed

Compare across

11 dimensions

Benzodiazepine

Chlordiazepoxide

First FDA approval: 1976-06-15

Benzodiazepine

Clonazepam

Brand: Klonopin

First FDA approval: 1975-06-02

Lowest NADACAcquisition cost floor across all NDCs

$0.142Per unit

$0.021Per unit

Average NADACAcross all dosage forms and strengths

$0.164Up to $0.188

$0.298Up to $3.88

Generic manufacturersActive ANDA holders — FDA Orange Book

39 total ANDAs filed

1139 total ANDAs filed

Annualized Part D spendCY2024 — CMS Part D Spending Dashboard

$1.5MFull year

$113.3MFull year

Part D claims (CY24)Total fills, all strengths

145K44K beneficiaries

13.2M2.4M beneficiaries

Avg cost per claimCalculated: total spend ÷ total claims

$10Per claim, all NDCs

$9Per claim, all NDCs

Part D plans surveyed2026 plan year — CMS Formulary file

329Across CMS plan year

Prior-authorization frictionPlan-NDC pairs requiring PA

30Minimal friction

56Minimal friction

Step therapy appliedPlan-NDC pairs requiring step therapy

0None

10Limited friction

FDA shortage statusLive cross-reference vs FDA Drug Shortage Database

NoneClear

Active shortageSee drug profile

Generic availableFDA Orange Book

Yes3 manufacturers

Yes11 manufacturers