Insulin Lispro-Aabc vs Insulin Aspart — Cost, Coverage & Plan Comparison

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Up to 4 drugsCross-class or same-class

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Federal data onlyNo PBM pricing assumed

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11 dimensions

Insulin Analog

Insulin Lispro-Aabc

Brand: LYUMJEV

First FDA approval: 2020-06-15

Insulin Analog

Insulin Aspart

Brand: .Insulin Aspart Protamine and Insulin Aspart

First FDA approval: 2001-08-27

Lowest NADACAcquisition cost floor across all NDCs

$7.89Per unit

$6.94Per unit

Average NADACAcross all dosage forms and strengths

$12.13Up to $20.32

$8.12Up to $8.96

Generic manufacturersActive ANDA holders — FDA Orange Book

00 total ANDAs filed

Annualized Part D spendCY2024 — CMS Part D Spending Dashboard

$139.8MFull year

$704.9MFull year

Part D claims (CY24)Total fills, all strengths

154K56K beneficiaries

3.4M1.3M beneficiaries

Avg cost per claimCalculated: total spend ÷ total claims

$909Per claim, all NDCs

$205Per claim, all NDCs

Part D plans surveyed2026 plan year — CMS Formulary file

329Across CMS plan year

Prior-authorization frictionPlan-NDC pairs requiring PA

33Minimal friction

92Minimal friction

Step therapy appliedPlan-NDC pairs requiring step therapy

0None

10Limited friction

FDA shortage statusLive cross-reference vs FDA Drug Shortage Database

DiscontinuedSee drug profile

Generic availableFDA Orange Book

NoBrand-only