Meropenem-Vaborbactam vs Meropenem — Cost, Coverage & Plan Comparison

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Up to 4 drugsCross-class or same-class

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Federal data onlyNo PBM pricing assumed

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11 dimensions

beta Lactamase Inhibitor

Meropenem-Vaborbactam

Brand: VABOMERE

First FDA approval: 2017-10-02

Penem Antibacterial

Meropenem

First FDA approval: 2011-10-14

Lowest NADACAcquisition cost floor across all NDCs

—Per unit

$5.84Per unit

Average NADACAcross all dosage forms and strengths

—

$5.84Up to $5.84

Generic manufacturersActive ANDA holders — FDA Orange Book

00 total ANDAs filed

819 total ANDAs filed

Annualized Part D spendCY2024 — CMS Part D Spending Dashboard

—Full year

$26.3MFull year

Part D claims (CY24)Total fills, all strengths

—— beneficiaries

144K48K beneficiaries

Avg cost per claimCalculated: total spend ÷ total claims

—Per claim, all NDCs

$183Per claim, all NDCs

Part D plans surveyed2026 plan year — CMS Formulary file

329Across CMS plan year

Prior-authorization frictionPlan-NDC pairs requiring PA

1Minimal friction

40Minimal friction

Step therapy appliedPlan-NDC pairs requiring step therapy

0None

FDA shortage statusLive cross-reference vs FDA Drug Shortage Database

NoneClear

Generic availableFDA Orange Book

NoBrand-only

Yes8 manufacturers