Moxifloxacin vs Levofloxacin — Cost, Coverage & Plan Comparison

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Up to 4 drugsCross-class or same-class

Start with the molecules your plan spends the most on. Most useful comparisons live within the same therapeutic class — switching across classes requires deeper clinical review.

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Federal data onlyNo PBM pricing assumed

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11 dimensions

Fluoroquinolone Antibacterial

Moxifloxacin

Brand: Moxifloxacin

First FDA approval: 2003-05-07

Fluoroquinolone Antibacterial

Levofloxacin

First FDA approval: 2010-11-10

Lowest NADACAcquisition cost floor across all NDCs

$1.73Per unit

$0.109Per unit

Average NADACAcross all dosage forms and strengths

$3.33Up to $31.77

$0.449Up to $2.36

Generic manufacturersActive ANDA holders — FDA Orange Book

2021 total ANDAs filed

2157 total ANDAs filed

Annualized Part D spendCY2024 — CMS Part D Spending Dashboard

$41.8MFull year

$23.6MFull year

Part D claims (CY24)Total fills, all strengths

1.7M1.1M beneficiaries

3.8M2.9M beneficiaries

Avg cost per claimCalculated: total spend ÷ total claims

$25Per claim, all NDCs

$6Per claim, all NDCs

Part D plans surveyed2026 plan year — CMS Formulary file

329Across CMS plan year

Prior-authorization frictionPlan-NDC pairs requiring PA

34Minimal friction

54Minimal friction

Step therapy appliedPlan-NDC pairs requiring step therapy

0None

FDA shortage statusLive cross-reference vs FDA Drug Shortage Database

DiscontinuedSee drug profile

NoneClear

Generic availableFDA Orange Book

Yes20 manufacturers

Yes21 manufacturers