Prednisone vs Triamcinolone Acetonide — Cost, Coverage & Plan Comparison

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Up to 4 drugsCross-class or same-class

Start with the molecules your plan spends the most on. Most useful comparisons live within the same therapeutic class — switching across classes requires deeper clinical review.

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Side by side, line by line.

Federal data onlyNo PBM pricing assumed

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11 dimensions

Corticosteroid

Prednisone

First FDA approval: 1972-04-21

Corticosteroid

Triamcinolone Acetonide

Brand: KENALOG-10

First FDA approval: 1978-02-14

Lowest NADACAcquisition cost floor across all NDCs

$0.037Per unit

$0.024Per unit

Average NADACAcross all dosage forms and strengths

$0.115Up to $0.613

$1.87Up to $17.84

Generic manufacturersActive ANDA holders — FDA Orange Book

1356 total ANDAs filed

2770 total ANDAs filed

Annualized Part D spendCY2024 — CMS Part D Spending Dashboard

$118.1MFull year

$105.6MFull year

Part D claims (CY24)Total fills, all strengths

24.2M12.7M beneficiaries

10.1M6.3M beneficiaries

Avg cost per claimCalculated: total spend ÷ total claims

$5Per claim, all NDCs

$10Per claim, all NDCs

Part D plans surveyed2026 plan year — CMS Formulary file

329Across CMS plan year

Prior-authorization frictionPlan-NDC pairs requiring PA

1052Substantial friction

0Zero PA friction

Step therapy appliedPlan-NDC pairs requiring step therapy

0None

FDA shortage statusLive cross-reference vs FDA Drug Shortage Database

NoneClear

Active shortageSee drug profile

Generic availableFDA Orange Book

Yes13 manufacturers

Yes27 manufacturers