Quetiapine vs Aripiprazole Orally Disintegrating — Cost, Coverage & Plan Comparison

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Up to 4 drugsCross-class or same-class

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Federal data onlyNo PBM pricing assumed

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11 dimensions

Atypical Antipsychotic

Quetiapine

Brand: Quetiapine Fumarate

First FDA approval: 1997-10-01

Atypical Antipsychotic

Aripiprazole Orally Disintegrating

Brand: Aripiprazole

First FDA approval: 2018-04-18

Lowest NADACAcquisition cost floor across all NDCs

$0.029Per unit

$2.87Per unit

Average NADACAcross all dosage forms and strengths

$0.749Up to $23.98

$3.30Up to $3.74

Generic manufacturersActive ANDA holders — FDA Orange Book

16132 total ANDAs filed

00 total ANDAs filed

Annualized Part D spendCY2024 — CMS Part D Spending Dashboard

$315.0MFull year

—Full year

Part D claims (CY24)Total fills, all strengths

14.8M2.7M beneficiaries

—— beneficiaries

Avg cost per claimCalculated: total spend ÷ total claims

$21Per claim, all NDCs

—Per claim, all NDCs

Part D plans surveyed2026 plan year — CMS Formulary file

329Across CMS plan year

Prior-authorization frictionPlan-NDC pairs requiring PA

794Substantial friction

80Minimal friction

Step therapy appliedPlan-NDC pairs requiring step therapy

5Limited friction

113Limited friction

FDA shortage statusLive cross-reference vs FDA Drug Shortage Database

NoneClear

Generic availableFDA Orange Book

Yes16 manufacturers

NoBrand-only