Ropinirole vs Pramipexole Dihydrochloride — Cost, Coverage & Plan Comparison

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Up to 4 drugsCross-class or same-class

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Federal data onlyNo PBM pricing assumed

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11 dimensions

Nonergot Dopamine Agonist

Ropinirole

First FDA approval: 2010-02-25

Nonergot Dopamine Agonist

Pramipexole Dihydrochloride

First FDA approval: 2010-10-08

Lowest NADACAcquisition cost floor across all NDCs

$0.043Per unit

$0.041Per unit

Average NADACAcross all dosage forms and strengths

$0.403Up to $2.29

$0.929Up to $2.84

Generic manufacturersActive ANDA holders — FDA Orange Book

1391 total ANDAs filed

1694 total ANDAs filed

Annualized Part D spendCY2024 — CMS Part D Spending Dashboard

$97.6MFull year

—Full year

Part D claims (CY24)Total fills, all strengths

5.2M1.3M beneficiaries

—— beneficiaries

Avg cost per claimCalculated: total spend ÷ total claims

$19Per claim, all NDCs

—Per claim, all NDCs

Part D plans surveyed2026 plan year — CMS Formulary file

329Across CMS plan year

Prior-authorization frictionPlan-NDC pairs requiring PA

0Zero PA friction

Step therapy appliedPlan-NDC pairs requiring step therapy

0None

21Limited friction

FDA shortage statusLive cross-reference vs FDA Drug Shortage Database

NoneClear

Generic availableFDA Orange Book

Yes13 manufacturers

Yes16 manufacturers