Tazarotene vs Adapalene and Benzoyl Peroxide Gel, — Cost, Coverage & Plan Comparison

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Up to 4 drugsCross-class or same-class

Start with the molecules your plan spends the most on. Most useful comparisons live within the same therapeutic class — switching across classes requires deeper clinical review.

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Federal data onlyNo PBM pricing assumed

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11 dimensions

Retinoid

Tazarotene

Brand: Arazlo

First FDA approval: 2017-03-10

Retinoid

Adapalene and Benzoyl Peroxide Gel,

First FDA approval: 2023-08-14

Lowest NADACAcquisition cost floor across all NDCs

$1.84Per unit

$0.285Per unit

Average NADACAcross all dosage forms and strengths

$6.57Up to $12.49

$0.285Up to $0.285

Generic manufacturersActive ANDA holders — FDA Orange Book

411 total ANDAs filed

00 total ANDAs filed

Annualized Part D spendCY2024 — CMS Part D Spending Dashboard

$6.1MFull year

—Full year

Part D claims (CY24)Total fills, all strengths

21K12K beneficiaries

—— beneficiaries

Avg cost per claimCalculated: total spend ÷ total claims

$285Per claim, all NDCs

—Per claim, all NDCs

Part D plans surveyed2026 plan year — CMS Formulary file

329Across CMS plan year

Prior-authorization frictionPlan-NDC pairs requiring PA

588Substantial friction

—Zero PA friction

Step therapy appliedPlan-NDC pairs requiring step therapy

7Limited friction

—None

FDA shortage statusLive cross-reference vs FDA Drug Shortage Database

NoneClear

Generic availableFDA Orange Book

Yes4 manufacturers

NoBrand-only