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Live data · NADAC + Part D CY24 · reviewed daily

Alprostadil (Caverject)

Alprostadil mimics prostaglandin effects, used in glaucoma treatment or labor induction depending on formulation.

First FDA approval1981-10-16
Generic availableYes · 2 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$10,693 in CY2024 Part D spend12 claims · — beneficiaries · 329 plans surveyed

Lowest NADAC
$82.49/unit
4 NDCs benchmarked, lowest of all strengths.
Average NADAC
$152.13
Across all dosage forms in distribution.
Highest NADAC
$236.76
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Alprostadil used for?

Alprostadil mimics prostaglandin effects, used in glaucoma treatment or labor induction depending on formulation.

Is there a generic for Alprostadil?

Yes. 2 ANDAs filed at FDA, 2 generic manufacturers currently shipping.

How much does my plan pay for Alprostadil?

Across 329 Part D plans, Alprostadil averages $152.13/unit (NADAC). Lowest available: $82.49/unit. Highest in distribution: $236.76/unit.

Is Alprostadil on the FDA shortage list?

No. Alprostadil is not currently on the FDA Drug Shortage Database.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Prostaglandin Analog6 alternatives in D1
01
Bimatoprost
Brand: DURYSTA
$7.19Lowest NADAC
9Generic mfrs
$969.1MCY24 Part D spend
Compare →
02
Carboprost Tromethamine
Brand: Hemabate
Lowest NADAC
11Generic mfrs
CY24 Part D spend
Compare →
03
Dinoprostone
Brand: CERVIDIL
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
04
Latanoprost
Brand: XALATAN
$1.20Lowest NADAC
8Generic mfrs
$204.7MCY24 Part D spend
Compare →
05
Latanoprost Ophthalmic Solution
Brand: IYUZEH
$10.12Lowest NADAC
0Generic mfrs
CY24 Part D spend
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06
Netarsudil and Latanoprost Ophthalmic Solution,
Brand: Rocklatan
$139.64Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (4 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.