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Live data · NADAC + Part D CY24 · reviewed daily

Amoxapine

Amoxapine treats depression and chronic pain by blocking reuptake of serotonin and norepinephrine.

First FDA approval1991-06-28
Generic availableYes · 2 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$278,639 in CY2024 Part D spend3K claims · 746 beneficiaries · 329 plans surveyed

Lowest NADAC
/unit
0 NDCs benchmarked, lowest of all strengths.
Average NADAC
Across all dosage forms in distribution.
Highest NADAC
Range is tight.
Plans with PA
316 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema9 entries indexed · 4 visible
What is Amoxapine used for?

Amoxapine treats depression and chronic pain by blocking reuptake of serotonin and norepinephrine.

Is there a generic for Amoxapine?

Yes. 8 ANDAs filed at FDA, 2 generic manufacturers currently shipping.

How much does my plan pay for Amoxapine?

NADAC pricing data not currently available for this drug.

Is Amoxapine on the FDA shortage list?

No. Amoxapine is not currently on the FDA Drug Shortage Database.

5 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Tricyclic Antidepressant6 alternatives in D1
01
Amitriptyline
Tricyclic Antidepressant
$0.035Lowest NADAC
10Generic mfrs
$82.0MCY24 Part D spend
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02
Clomipramine
Brand: ANAFRANIL
$0.203Lowest NADAC
13Generic mfrs
$22.2MCY24 Part D spend
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03
Desipramine
Brand: Desipramine Hydrochloride
$0.146Lowest NADAC
5Generic mfrs
$4.9MCY24 Part D spend
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04
Doxepin
Brand: Doxepin
$0.078Lowest NADAC
25Generic mfrs
$99.4MCY24 Part D spend
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05
Imipramine
Tricyclic Antidepressant
$0.083Lowest NADAC
7Generic mfrs
$6.9MCY24 Part D spend
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06
Nortriptyline
Brand: PAMELOR
$0.123Lowest NADAC
5Generic mfrs
$31.8MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (8 approvals on file) · NADAC unit costs: CMS NADAC weekly file · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.