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Live data · NADAC + Part D CY24 · reviewed daily

Atovaquone and Proguanil (MALARONE)

Antimalarial class · 2 generic manufacturers · 4 ANDAs filed at FDA.

First FDA approval2000-07-26
Generic availableYes · 2 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$1.29/unit
8 NDCs benchmarked, lowest of all strengths.
Average NADAC
$1.47
Across all dosage forms in distribution.
Highest NADAC
$1.50
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema10 entries indexed · 4 visible
What is Atovaquone and Proguanil used for?

Atovaquone and Proguanil is a Antimalarial medication tracked in Medicare Part D.

Is there a generic for Atovaquone and Proguanil?

Yes. 4 ANDAs filed at FDA, 2 generic manufacturers currently shipping.

How much does my plan pay for Atovaquone and Proguanil?

Across 329 Part D plans, Atovaquone and Proguanil averages $1.47/unit (NADAC). Lowest available: $1.29/unit. Highest in distribution: $1.50/unit.

Is Atovaquone and Proguanil on the FDA shortage list?

No. Atovaquone and Proguanil is not currently on the FDA Drug Shortage Database.

6 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Antimalarial5 alternatives in D1
01
Atovaquone
Brand: MEPRON
$0.719Lowest NADAC
7Generic mfrs
$60.4MCY24 Part D spend
Compare →
02
Atovaquone Oral Suspension
Brand: ATOVAQUONE
$0.719Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
03
Atovaquone and Proguanil Hydrochloride Pediatric
Antimalarial
$1.29Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
04
Chloroquine
Antimalarial
$2.48Lowest NADAC
4Generic mfrs
$591,313CY24 Part D spend
Compare →
05
Quinine
Brand: Quinine Sulfate
$0.774Lowest NADAC
4Generic mfrs
$418,980CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (6 approvals on file) · NADAC unit costs: CMS NADAC weekly file (8 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.