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Live data · NADAC + Part D CY24 · reviewed daily

Avalglucosidase Alfa-Ngpt (Nexviazyme)

Hydrolytic Lysosomal Glycogen-specific Enzyme class · 0 generic manufacturers · 0 ANDAs filed at FDA.

First FDA approval2021-08-06
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$55.5M in CY2024 Part D spend951 claims · 105 beneficiaries · 329 plans surveyed

Lowest NADAC
/unit
0 NDCs benchmarked, lowest of all strengths.
Average NADAC
Across all dosage forms in distribution.
Highest NADAC
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema10 entries indexed · 4 visible
What is Avalglucosidase Alfa-Ngpt used for?

Avalglucosidase Alfa-Ngpt is a Hydrolytic Lysosomal Glycogen-specific Enzyme medication tracked in Medicare Part D.

Is there a generic for Avalglucosidase Alfa-Ngpt?

No. Avalglucosidase Alfa-Ngpt is brand-only with no generic equivalents currently in market.

How much does my plan pay for Avalglucosidase Alfa-Ngpt?

NADAC pricing data not currently available for this drug.

Is Avalglucosidase Alfa-Ngpt on the FDA shortage list?

No. Avalglucosidase Alfa-Ngpt is not currently on the FDA Drug Shortage Database.

6 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Hydrolytic Lysosomal Glycogen-specific Enzyme1 alternative in D1
01
Alglucosidase Alfa
Brand: Lumizyme
Lowest NADAC
0Generic mfrs
$19.8MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book · NADAC unit costs: CMS NADAC weekly file · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.