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Live data · NADAC + Part D CY24 · reviewed daily

Brimonidine (ALPHAGAN P)

Brimonidine stimulates alpha-adrenergic receptors, used for nasal congestion, glaucoma, or ADHD.

First FDA approval2001-07-10
Generic availableYes · 11 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$267.0M in CY2024 Part D spend4.1M claims · 1.3M beneficiaries · 329 plans surveyed

Lowest NADAC
$0.525/unit
20 NDCs benchmarked, lowest of all strengths.
Average NADAC
$4.62
Across all dosage forms in distribution.
Highest NADAC
$10.66
Wide spread — brand-strength NDCs still in market.
Plans with PA
3 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema12 entries indexed · 4 visible
What is Brimonidine used for?

Brimonidine stimulates alpha-adrenergic receptors, used for nasal congestion, glaucoma, or ADHD.

Is there a generic for Brimonidine?

Yes. 16 ANDAs filed at FDA, 11 generic manufacturers currently shipping.

How much does my plan pay for Brimonidine?

Across 329 Part D plans, Brimonidine averages $4.62/unit (NADAC). Lowest available: $0.525/unit. Highest in distribution: $10.66/unit.

Is Brimonidine on the FDA shortage list?

No. Brimonidine is not currently on the FDA Drug Shortage Database.

8 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

alpha-Adrenergic Agonist6 alternatives in D1
01
Adrenalin (Epinephrine)
alpha-Adrenergic Agonist
Lowest NADAC
0Generic mfrs
CY24 Part D spend
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02
Adrenalin(R)
alpha-Adrenergic Agonist
Lowest NADAC
0Generic mfrs
CY24 Part D spend
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03
Auvi-Q
alpha-Adrenergic Agonist
$297.57Lowest NADAC
0Generic mfrs
CY24 Part D spend
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04
Brimonidine and Timolol
Brand: Brimonidine Tartrate/Timolol Maleate
$2.30Lowest NADAC
0Generic mfrs
CY24 Part D spend
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05
Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide
Brand: Brompheniramine Maleate, Pseudoephedrine Hydrochloride and Dextromethorphan Hydrobromide
$0.074Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
06
Ephedrine
Brand: Akovaz
Lowest NADAC
12Generic mfrs
$251CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (20 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.