A BuiltForAI Property
Live data · NADAC + Part D CY24 · reviewed daily

Brinzolamide and Brimonidine (SIMBRINZA)

Carbonic Anhydrase Inhibitor class · 0 generic manufacturers · 0 ANDAs filed at FDA.

First FDA approval2013-05-06
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$26.07/unit
1 NDCs benchmarked, lowest of all strengths.
Average NADAC
$26.07
Across all dosage forms in distribution.
Highest NADAC
$26.07
Range is tight.
Plans with PA
2 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Brinzolamide and Brimonidine used for?

Brinzolamide and Brimonidine is a Carbonic Anhydrase Inhibitor medication tracked in Medicare Part D.

Is there a generic for Brinzolamide and Brimonidine?

No. Brinzolamide and Brimonidine is brand-only with no generic equivalents currently in market.

How much does my plan pay for Brinzolamide and Brimonidine?

Across 329 Part D plans, Brinzolamide and Brimonidine averages $26.07/unit (NADAC). Lowest available: $26.07/unit. Highest in distribution: $26.07/unit.

Is Brinzolamide and Brimonidine on the FDA shortage list?

No. Brinzolamide and Brimonidine is not currently on the FDA Drug Shortage Database.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Carbonic Anhydrase Inhibitor6 alternatives in D1
01
Acetazolamide
Brand: Acetazolamide
$0.100Lowest NADAC
26Generic mfrs
$22.7MCY24 Part D spend
Compare →
02
Acetazolamide Extended-Release
Carbonic Anhydrase Inhibitor
$0.290Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
03
Brinzolamide
Brand: Azopt
$10.16Lowest NADAC
2Generic mfrs
$75.2MCY24 Part D spend
Compare →
04
Dichlorphenamide
Brand: Keveyis
Lowest NADAC
2Generic mfrs
$37.3MCY24 Part D spend
Compare →
05
Dorzolamide
Brand: Dorzolamide Hydrochloride
$0.897Lowest NADAC
9Generic mfrs
$32.3MCY24 Part D spend
Compare →
06
Dorzolamide and Timolol
Brand: COSOPT
$0.943Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (1 approvals on file) · NADAC unit costs: CMS NADAC weekly file (1 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.