Live data · NADAC + Part D CY24 · reviewed daily

Butalbital, Acetaminophen, Caffeine and Codeine

Barbiturate class · 2 generic manufacturers · 4 ANDAs filed at FDA.

First FDA approval2004-07-01
Generic availableYes · 2 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$0.806/unit
3 NDCs benchmarked, lowest of all strengths.
Average NADAC
$2.32
Across all dosage forms in distribution.
Highest NADAC
$5.34
Wide spread — brand-strength NDCs still in market.
Plans with PA
46 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema9 entries indexed · 4 visible
What is Butalbital, Acetaminophen, Caffeine and Codeine used for?

Butalbital, Acetaminophen, Caffeine and Codeine is a Barbiturate medication tracked in Medicare Part D.

Is there a generic for Butalbital, Acetaminophen, Caffeine and Codeine?

Yes. 4 ANDAs filed at FDA, 2 generic manufacturers currently shipping.

How much does my plan pay for Butalbital, Acetaminophen, Caffeine and Codeine?

Across 329 Part D plans, Butalbital, Acetaminophen, Caffeine and Codeine averages $2.32/unit (NADAC). Lowest available: $0.806/unit. Highest in distribution: $5.34/unit.

Is Butalbital, Acetaminophen, Caffeine and Codeine on the FDA shortage list?

No. Butalbital, Acetaminophen, Caffeine and Codeine is not currently on the FDA Drug Shortage Database.

5 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Barbiturate6 alternatives in D1
01
Butal/Apap/Caff
Barbiturate
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
02
Butal/Apap/Caffeine
Barbiturate
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
03
$0.578Lowest NADAC
8Generic mfrs
CY24 Part D spend
Compare →
04
Butalbital and Acetaminophen Tablets
Brand: Butalbital and Acetaminophen
Lowest NADAC
0Generic mfrs
CY24 Part D spend
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05
$0.122Lowest NADAC
15Generic mfrs
CY24 Part D spend
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06
Butalbital, Acetaminophen, and Caffeine Capsules
Brand: Butalbital, Acetaminophen, and Caffeine
$0.336Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh14 Jul 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (5 approvals on file) · NADAC unit costs: CMS NADAC weekly file (3 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.