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Live data · NADAC + Part D CY24 · reviewed daily

Cefazolin (CEFAZOLIN)

Cefazolin kills bacteria by disrupting cell wall synthesis, used for a range of infections.

First FDA approval1988-12-09
Generic availableYes · 5 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$6.5M in CY2024 Part D spend122K claims · 31K beneficiaries · 329 plans surveyed

Lowest NADAC
$0.987/unit
10 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.987
Across all dosage forms in distribution.
Highest NADAC
$0.987
Range is tight.
Plans with PA
2 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema9 entries indexed · 4 visible
What is Cefazolin used for?

Cefazolin kills bacteria by disrupting cell wall synthesis, used for a range of infections.

Is there a generic for Cefazolin?

Yes. 16 ANDAs filed at FDA, 5 generic manufacturers currently shipping.

How much does my plan pay for Cefazolin?

Across 329 Part D plans, Cefazolin averages $0.987/unit (NADAC). Lowest available: $0.987/unit. Highest in distribution: $0.987/unit.

Is Cefazolin on the FDA shortage list?

No. Cefazolin is not currently on the FDA Drug Shortage Database.

5 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Cephalosporin Antibacterial6 alternatives in D1
01
Cefaclor
Cephalosporin Antibacterial
$0.874Lowest NADAC
2Generic mfrs
$825,749CY24 Part D spend
Compare →
02
Cefadroxil
Cephalosporin Antibacterial
$0.193Lowest NADAC
0Generic mfrs
$11.3MCY24 Part D spend
Compare →
03
Cefdinir
Cephalosporin Antibacterial
$0.104Lowest NADAC
6Generic mfrs
$54.7MCY24 Part D spend
Compare →
04
Cefepime
Brand: CEFEPIME HYDROCHLORIDE AND DEXTROSE
$3.73Lowest NADAC
5Generic mfrs
$27.5MCY24 Part D spend
Compare →
05
Cefixime
Cephalosporin Antibacterial
$2.25Lowest NADAC
5Generic mfrs
$2.8MCY24 Part D spend
Compare →
06
Cefotetan
Brand: Cefotan
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (10 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.