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Live data · NADAC + Part D CY24 · reviewed daily

Cefepime (CEFEPIME HYDROCHLORIDE AND DEXTROSE)

Cefepime kills bacteria by disrupting cell wall synthesis, used for a range of infections.

First FDA approval2008-05-01
Generic availableYes · 5 mfrs
Shortage statusDiscontinued
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$27.5M in CY2024 Part D spend150K claims · 51K beneficiaries · 329 plans surveyed

Lowest NADAC
$3.73/unit
8 NDCs benchmarked, lowest of all strengths.
Average NADAC
$3.73
Across all dosage forms in distribution.
Highest NADAC
$3.73
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Cefepime used for?

Cefepime kills bacteria by disrupting cell wall synthesis, used for a range of infections.

Is there a generic for Cefepime?

Yes. 10 ANDAs filed at FDA, 5 generic manufacturers currently shipping.

How much does my plan pay for Cefepime?

Across 329 Part D plans, Cefepime averages $3.73/unit (NADAC). Lowest available: $3.73/unit. Highest in distribution: $3.73/unit.

Is Cefepime on the FDA shortage list?

Cefepime has been discontinued by its manufacturer(s).

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Cephalosporin Antibacterial6 alternatives in D1
01
Cefaclor
Cephalosporin Antibacterial
$0.874Lowest NADAC
2Generic mfrs
$825,749CY24 Part D spend
Compare →
02
Cefadroxil
Cephalosporin Antibacterial
$0.193Lowest NADAC
0Generic mfrs
$11.3MCY24 Part D spend
Compare →
03
Cefazolin
Brand: CEFAZOLIN
$0.987Lowest NADAC
5Generic mfrs
$6.5MCY24 Part D spend
Compare →
04
Cefdinir
Cephalosporin Antibacterial
$0.104Lowest NADAC
6Generic mfrs
$54.7MCY24 Part D spend
Compare →
05
Cefixime
Cephalosporin Antibacterial
$2.25Lowest NADAC
5Generic mfrs
$2.8MCY24 Part D spend
Compare →
06
Cefotetan
Brand: Cefotan
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (8 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.