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Live data · NADAC + Part D CY24 · reviewed daily

Cetirizine (Cetirizine Hydrochloride)

Cetirizine blocks histamine to relieve allergy symptoms like sneezing, itching, and runny nose.

First FDA approval2008-07-24
Generic availableYes · 9 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$5.5M in CY2024 Part D spend35K claims · 14K beneficiaries · 329 plans surveyed

Lowest NADAC
$0.021/unit
10 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.819
Across all dosage forms in distribution.
Highest NADAC
$7.34
Wide spread — brand-strength NDCs still in market.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema12 entries indexed · 4 visible
What is Cetirizine used for?

Cetirizine blocks histamine to relieve allergy symptoms like sneezing, itching, and runny nose.

Is there a generic for Cetirizine?

Yes. 9 ANDAs filed at FDA, 9 generic manufacturers currently shipping.

How much does my plan pay for Cetirizine?

Across 329 Part D plans, Cetirizine averages $0.819/unit (NADAC). Lowest available: $0.021/unit. Highest in distribution: $7.34/unit.

Is Cetirizine on the FDA shortage list?

No. Cetirizine is not currently on the FDA Drug Shortage Database.

8 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Histamine-1 Receptor Antagonist6 alternatives in D1
01
Alcaftadine
Brand: LASTACAFT
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
02
Azelastine
Brand: Azelastine Hydrochloride
$0.286Lowest NADAC
10Generic mfrs
$131.8MCY24 Part D spend
Compare →
03
Azelastine and Fluticasone
Brand: DYMISTA
$2.26Lowest NADAC
0Generic mfrs
CY24 Part D spend
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04
Bepotastine Besilate
Brand: Bepreve
$13.03Lowest NADAC
4Generic mfrs
$16.6MCY24 Part D spend
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05
Carbinoxamine
Brand: CARBZAH
$0.432Lowest NADAC
4Generic mfrs
$3.6MCY24 Part D spend
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06
Desloratadine
Brand: Clarinex
$0.287Lowest NADAC
6Generic mfrs
$10.5MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (10 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.