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Live data · NADAC + Part D CY24 · reviewed daily

Chlorthalidone (HEMICLOR)

INDICATIONS AND USAGE Diuretics such as chlorthalidone are indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs ....

First FDA approval1981-02-26
Generic availableYes · 16 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$71.4M in CY2024 Part D spend4.4M claims · 1.5M beneficiaries · 329 plans surveyed

Lowest NADAC
$0.085/unit
20 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.085
Across all dosage forms in distribution.
Highest NADAC
$0.085
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema12 entries indexed · 4 visible
What is Chlorthalidone used for?

INDICATIONS AND USAGE Diuretics such as chlorthalidone are indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs ....

Is there a generic for Chlorthalidone?

Yes. 32 ANDAs filed at FDA, 16 generic manufacturers currently shipping.

How much does my plan pay for Chlorthalidone?

Across 329 Part D plans, Chlorthalidone averages $0.085/unit (NADAC). Lowest available: $0.085/unit. Highest in distribution: $0.085/unit.

Is Chlorthalidone on the FDA shortage list?

No. Chlorthalidone is not currently on the FDA Drug Shortage Database.

8 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Thiazide-like Diuretic5 alternatives in D1
01
Atenolol and Chlorthalidone
Brand: TENORETIC
$0.265Lowest NADAC
5Generic mfrs
CY24 Part D spend
Compare →
02
Atenolol and Chlorthalidone Tablet
Brand: ATENOLOL AND CHLORTHALIDONE
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
03
Azilsartan Kamedoxomil and Chlorthalidone
Brand: Edarbyclor
$8.49Lowest NADAC
1Generic mfrs
CY24 Part D spend
Compare →
04
Indapamide
Thiazide-like Diuretic
$0.105Lowest NADAC
3Generic mfrs
$7.8MCY24 Part D spend
Compare →
05
Metolazone
Thiazide-like Diuretic
$0.222Lowest NADAC
10Generic mfrs
$20.8MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (20 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.