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Live data · NADAC + Part D CY24 · reviewed daily

Cobicistat (Tybost)

Cytochrome P450 3A Inhibitor class · 0 generic manufacturers · 0 ANDAs filed at FDA.

First FDA approval2014-09-24
Generic availableNo (brand-only)
Shortage statusDiscontinued
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$391,226 in CY2024 Part D spend1K claims · 238 beneficiaries · 329 plans surveyed

Lowest NADAC
/unit
0 NDCs benchmarked, lowest of all strengths.
Average NADAC
Across all dosage forms in distribution.
Highest NADAC
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema12 entries indexed · 4 visible
What is Cobicistat used for?

Cobicistat is a Cytochrome P450 3A Inhibitor medication tracked in Medicare Part D.

Is there a generic for Cobicistat?

No. Cobicistat is brand-only with no generic equivalents currently in market.

How much does my plan pay for Cobicistat?

NADAC pricing data not currently available for this drug.

Is Cobicistat on the FDA shortage list?

Cobicistat has been discontinued by its manufacturer(s).

8 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Cytochrome P450 3A Inhibitor6 alternatives in D1
01
Atazanavir and Cobicistat
Brand: EVOTAZ
$51.98Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
02
Darunavir Ethanolate and Cobicistat
Brand: PREZCOBIX
$79.99Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
03
Darunavir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide
Brand: Symtuza
$152.95Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
04
Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide
Brand: Genvoya
$143.35Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
05
Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Disoproxil
Brand: Stribild
$150.41Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
06
Lopinavir and Ritonavir
Brand: Kaletra
$4.70Lowest NADAC
5Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (1 approvals on file) · NADAC unit costs: CMS NADAC weekly file · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.