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Estrogens, Conjugated (Conjugated Estrogens)

Estrogens, Conjugated supplements estrogen levels, used in hormone replacement therapy and contraception.

First FDA approval2004-09-01
Generic availableYes · 1 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$367.7M in CY2024 Part D spend897K claims · 383K beneficiaries · 329 plans surveyed

Lowest NADAC
$5.24/unit
12 NDCs benchmarked, lowest of all strengths.
Average NADAC
$6.51
Across all dosage forms in distribution.
Highest NADAC
$6.95
Range is tight.
Plans with PA
95 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Estrogens, Conjugated used for?

Estrogens, Conjugated supplements estrogen levels, used in hormone replacement therapy and contraception.

Is there a generic for Estrogens, Conjugated?

Yes. 5 ANDAs filed at FDA, 1 generic manufacturers currently shipping.

How much does my plan pay for Estrogens, Conjugated?

Across 329 Part D plans, Estrogens, Conjugated averages $6.51/unit (NADAC). Lowest available: $5.24/unit. Highest in distribution: $6.95/unit.

Is Estrogens, Conjugated on the FDA shortage list?

No. Estrogens, Conjugated is not currently on the FDA Drug Shortage Database.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Estrogen6 alternatives in D1
01
Estradiol
Brand: Climara
$0.059Lowest NADAC
21Generic mfrs
$605.7MCY24 Part D spend
Compare →
02
Norethindrone and Ethinyl Estradiol
Brand: ALYACEN 1/35
$0.128Lowest NADAC
17Generic mfrs
CY24 Part D spend
Compare →
03
Levonorgestrel and Ethinyl Estradiol
Brand: ALTAVERA
$0.112Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
04
Norethindrone and Ethinyl Estradiol and Ferrous
Brand: AUROVELA Fe
$0.128Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
05
Estradiol and Norethindrone
Brand: ABIGALE
$0.659Lowest NADAC
6Generic mfrs
CY24 Part D spend
Compare →
06
Conjugated Estrogens and Medroxyprogesterone
Brand: Premphase
$8.68Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (12 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.