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Live data · NADAC + Part D CY24 · reviewed daily

Cyanocobalamin (Nascobal)

Vitamin B12 class · 16 generic manufacturers · 17 ANDAs filed at FDA.

First FDA approval1971-10-20
Generic availableYes · 16 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$0.328/unit
20 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.766
Across all dosage forms in distribution.
Highest NADAC
$1.50
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Cyanocobalamin used for?

Cyanocobalamin is a Vitamin B12 medication tracked in Medicare Part D.

Is there a generic for Cyanocobalamin?

Yes. 17 ANDAs filed at FDA, 16 generic manufacturers currently shipping.

How much does my plan pay for Cyanocobalamin?

Across 329 Part D plans, Cyanocobalamin averages $0.766/unit (NADAC). Lowest available: $0.328/unit. Highest in distribution: $1.50/unit.

Is Cyanocobalamin on the FDA shortage list?

No. Cyanocobalamin is not currently on the FDA Drug Shortage Database.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Vitamin B125 alternatives in D1
01
Cyanocobalamine
Vitamin B12
$0.493Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
02
Cyanocobalamine Injection
Brand: CYANOCOBALAMINE
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
03
Ferrous Fumarate, Polysaccharide Iron Complex
Brand: PureVit DualFe Plus
$0.392Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
05
Multivitamin and Mineral
Brand: Se-Tan PLUS
$0.392Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (20 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.