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Live data · NADAC + Part D CY24 · reviewed daily

Cyclosporine Ophthalmic Solution (VEVYE)

Calcineurin Inhibitor Immunosuppressant class · 0 generic manufacturers · 0 ANDAs filed at FDA.

First FDA approval2023-12-01
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$368.54/unit
1 NDCs benchmarked, lowest of all strengths.
Average NADAC
$368.54
Across all dosage forms in distribution.
Highest NADAC
$368.54
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema9 entries indexed · 4 visible
What is Cyclosporine Ophthalmic Solution used for?

Cyclosporine Ophthalmic Solution is a Calcineurin Inhibitor Immunosuppressant medication tracked in Medicare Part D.

Is there a generic for Cyclosporine Ophthalmic Solution?

No. Cyclosporine Ophthalmic Solution is brand-only with no generic equivalents currently in market.

How much does my plan pay for Cyclosporine Ophthalmic Solution?

Across 329 Part D plans, Cyclosporine Ophthalmic Solution averages $368.54/unit (NADAC). Lowest available: $368.54/unit. Highest in distribution: $368.54/unit.

Is Cyclosporine Ophthalmic Solution on the FDA shortage list?

No. Cyclosporine Ophthalmic Solution is not currently on the FDA Drug Shortage Database.

5 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Calcineurin Inhibitor Immunosuppressant4 alternatives in D1
01
Cyclosporine
Brand: CEQUA
$0.310Lowest NADAC
15Generic mfrs
$2.51BCY24 Part D spend
Compare →
02
Pimecrolimus
Calcineurin Inhibitor Immunosuppressant
$2.69Lowest NADAC
2Generic mfrs
$27.2MCY24 Part D spend
Compare →
03
Tacrolimus
Brand: Envarsus
$0.154Lowest NADAC
15Generic mfrs
$156.6MCY24 Part D spend
Compare →
04
Voclosporin
Brand: LUPKYNIS
Lowest NADAC
0Generic mfrs
$41.3MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book · NADAC unit costs: CMS NADAC weekly file (1 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.