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Live data · NADAC + Part D CY24 · reviewed daily

Dexmedetomidine (Dexmedetomidine Hydrochloride in Sodium Chloride)

Central alpha-2 Adrenergic Agonist class · 24 generic manufacturers · 49 ANDAs filed at FDA.

First FDA approval2004-11-30
Generic availableYes · 24 mfrs
Shortage statusActive shortage
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$308,999 in CY2024 Part D spend97 claims · 42 beneficiaries · 329 plans surveyed

Lowest NADAC
/unit
0 NDCs benchmarked, lowest of all strengths.
Average NADAC
Across all dosage forms in distribution.
Highest NADAC
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Dexmedetomidine used for?

Dexmedetomidine is a Central alpha-2 Adrenergic Agonist medication tracked in Medicare Part D.

Is there a generic for Dexmedetomidine?

Yes. 49 ANDAs filed at FDA, 24 generic manufacturers currently shipping.

How much does my plan pay for Dexmedetomidine?

NADAC pricing data not currently available for this drug.

Is Dexmedetomidine on the FDA shortage list?

Yes. Dexmedetomidine is currently listed as an active FDA shortage.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Central alpha-2 Adrenergic Agonist4 alternatives in D1
01
Clonidine
Brand: Duraclon
$0.025Lowest NADAC
23Generic mfrs
$123.7MCY24 Part D spend
Compare →
02
Clonidine Transdermal System
Brand: Catapres-TTS-1
$7.23Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
03
Dexmedetomidine Hydrochloride In
Brand: Dexmedetomidine Hydrochloride
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
04
Guanfacine
Brand: GUANFACINE
$0.140Lowest NADAC
18Generic mfrs
$14.4MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.