A BuiltForAI Property
Live data · NADAC + Part D CY24 · reviewed daily

Diclofenac and Misoprostol (ARTHROTEC)

Prostaglandin E1 Analog class · 4 generic manufacturers · 8 ANDAs filed at FDA.

First FDA approval1997-12-24
Generic availableYes · 4 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$0.931/unit
15 NDCs benchmarked, lowest of all strengths.
Average NADAC
$1.50
Across all dosage forms in distribution.
Highest NADAC
$8.51
Wide spread — brand-strength NDCs still in market.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema10 entries indexed · 4 visible
What is Diclofenac and Misoprostol used for?

Diclofenac and Misoprostol is a Prostaglandin E1 Analog medication tracked in Medicare Part D.

Is there a generic for Diclofenac and Misoprostol?

Yes. 8 ANDAs filed at FDA, 4 generic manufacturers currently shipping.

How much does my plan pay for Diclofenac and Misoprostol?

Across 329 Part D plans, Diclofenac and Misoprostol averages $1.50/unit (NADAC). Lowest available: $0.931/unit. Highest in distribution: $8.51/unit.

Is Diclofenac and Misoprostol on the FDA shortage list?

No. Diclofenac and Misoprostol is not currently on the FDA Drug Shortage Database.

6 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Prostaglandin E1 Analog2 alternatives in D1
01
Dicloenac and Misoprostol
Prostaglandin E1 Analog
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
02
Misoprostol
Brand: Cytotec
$0.424Lowest NADAC
3Generic mfrs
$5.3MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (15 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.