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Live data · NADAC + Part D CY24 · reviewed daily

Divalproex (Depakote)

Divalproex sodium extended-release tablets are indicated for: • Acute treatment of manic or mixed episodes associated with bipolar disorder, with or without psychotic features ( 1.1 ) • Monotherapy....

First FDA approval1983-03-10
Generic availableYes · 21 mfrs
Shortage statusDiscontinued
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$362.1M in CY2024 Part D spend7.7M claims · 1.3M beneficiaries · 329 plans surveyed

Lowest NADAC
$0.055/unit
20 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.065
Across all dosage forms in distribution.
Highest NADAC
$0.086
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema12 entries indexed · 4 visible
What is Divalproex used for?

Divalproex sodium extended-release tablets are indicated for: • Acute treatment of manic or mixed episodes associated with bipolar disorder, with or without psychotic features ( 1.1 ) • Monotherapy....

Is there a generic for Divalproex?

Yes. 56 ANDAs filed at FDA, 21 generic manufacturers currently shipping.

How much does my plan pay for Divalproex?

Across 329 Part D plans, Divalproex averages $0.065/unit (NADAC). Lowest available: $0.055/unit. Highest in distribution: $0.086/unit.

Is Divalproex on the FDA shortage list?

Divalproex has been discontinued by its manufacturer(s).

8 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Mood Stabilizer2 alternatives in D1
01
Carbamazepine
Brand: Carbamazepin
$0.104Lowest NADAC
21Generic mfrs
$188.3MCY24 Part D spend
Compare →
02
Carbamazepine Er
Mood Stabilizer
$0.226Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (20 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.