Live data · NADAC + Part D CY24 · reviewed daily

Dupilumab (Dupixent)

Interleukin-4 Receptor alpha Antagonist class · 0 generic manufacturers · 0 ANDAs filed at FDA.

First FDA approval2017-03-28
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$4.56B in CY2024 Part D spend1.1M claims · 203K beneficiaries · 329 plans surveyed

Lowest NADAC
$1009.56/unit
4 NDCs benchmarked, lowest of all strengths.
Average NADAC
$1393.19
Across all dosage forms in distribution.
Highest NADAC
$1778.86
Range is tight.
Plans with PA
1311 / 329
Substantial PA friction across plans.

Questions a plan sponsor actually asks.

FAQPage schema9 entries indexed · 4 visible
What is Dupilumab used for?

Dupilumab is tracked in Medicare Part D. Specific indication information is not available in our current dataset.

Sources: CMS Part D Spending CY24 · CMS NADAC weekly · FDA Orange Book
Is there a generic for Dupilumab?

No. Dupilumab is brand-only with no generic equivalents currently in market.

Sources: CMS Part D Spending CY24 · CMS NADAC weekly · FDA Orange Book
How much does my plan pay for Dupilumab?

Across 329 Part D plans, Dupilumab averages $1393.19/unit (NADAC). Lowest available: $1009.56/unit. Highest in distribution: $1778.86/unit.

Sources: CMS Part D Spending CY24 · CMS NADAC weekly · FDA Orange Book
Is Dupilumab on the FDA shortage list?

No. Dupilumab is not currently on the FDA Drug Shortage Database.

Sources: CMS Part D Spending CY24 · CMS NADAC weekly · FDA Orange Book

5 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Related questions.

Q&A librarySourced · reviewed quarterly
pricingWhat is NADAC?pricingIs NADAC the same as my PBM cost?pricingWhat is spread pricing?pricingWhat is a NADAC pass-through PBM contract?pricingWhat's the difference between AWP, MAC, and NADAC?pricingWhat is a dispensing fee in a PBM contract?
Browse all canonical questions →

Sources · every number above traces back.

Last refresh15 Oct 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book · NADAC unit costs: CMS NADAC weekly file (4 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.