Live data · NADAC + Part D CY24 · reviewed daily

Empagliflozin and Metformin (Synjardy)

Sodium-Glucose Cotransporter 2 Inhibitor class · 0 generic manufacturers · 0 ANDAs filed at FDA.

First FDA approval2015-08-26
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$5.60/unit
8 NDCs benchmarked, lowest of all strengths.
Average NADAC
$5.60
Across all dosage forms in distribution.
Highest NADAC
$5.62
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema10 entries indexed · 4 visible
What is Empagliflozin and Metformin used for?

Empagliflozin and Metformin is a Sodium-Glucose Cotransporter 2 Inhibitor medication tracked in Medicare Part D.

Is there a generic for Empagliflozin and Metformin?

No. Empagliflozin and Metformin is brand-only with no generic equivalents currently in market.

How much does my plan pay for Empagliflozin and Metformin?

Across 329 Part D plans, Empagliflozin and Metformin averages $5.60/unit (NADAC). Lowest available: $5.60/unit. Highest in distribution: $5.62/unit.

Is Empagliflozin and Metformin on the FDA shortage list?

No. Empagliflozin and Metformin is not currently on the FDA Drug Shortage Database.

6 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Sodium-Glucose Cotransporter 2 Inhibitor6 alternatives in D1
01
Bexagliflozin
Brand: BRENZAVVY
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
02
Empagliflozin
Brand: JARDIANCE
$11.19Lowest NADAC
0Generic mfrs
$18.48BCY24 Part D spend
Compare →
03
$11.20Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
04
$5.62Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
05
Empagliflozin, Metformin
Brand: Synjardy
$5.60Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
06
Sotagliflozin
Brand: INPEFA
$20.50Lowest NADAC
0Generic mfrs
$9.3MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh14 Jul 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book · NADAC unit costs: CMS NADAC weekly file (8 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.