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Live data · NADAC + Part D CY24 · reviewed daily

Emtricitabine and Tenofovir Disoproxil (Truvada)

Emtricitabine and Tenofovir Disoproxil blocks HIV replication by inhibiting reverse transcriptase.

First FDA approval2004-08-02
Generic availableYes · 10 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$0.457/unit
18 NDCs benchmarked, lowest of all strengths.
Average NADAC
$5.37
Across all dosage forms in distribution.
Highest NADAC
$59.79
Wide spread — brand-strength NDCs still in market.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Emtricitabine and Tenofovir Disoproxil used for?

Emtricitabine and Tenofovir Disoproxil blocks HIV replication by inhibiting reverse transcriptase.

Is there a generic for Emtricitabine and Tenofovir Disoproxil?

Yes. 22 ANDAs filed at FDA, 10 generic manufacturers currently shipping.

How much does my plan pay for Emtricitabine and Tenofovir Disoproxil?

Across 329 Part D plans, Emtricitabine and Tenofovir Disoproxil averages $5.37/unit (NADAC). Lowest available: $0.457/unit. Highest in distribution: $59.79/unit.

Is Emtricitabine and Tenofovir Disoproxil on the FDA shortage list?

No. Emtricitabine and Tenofovir Disoproxil is not currently on the FDA Drug Shortage Database.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor6 alternatives in D1
01
Abacavir
Brand: Abacavir
$0.652Lowest NADAC
5Generic mfrs
$4.2MCY24 Part D spend
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02
Bictegravir Sodium, Emtricitabine, and Tenofovir Alafenamide
Brand: Biktarvy
$136.73Lowest NADAC
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Emtricitabine
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$14.51Lowest NADAC
2Generic mfrs
$3.0MCY24 Part D spend
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04
Emtricitabine and Tdf
Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor
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0Generic mfrs
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05
Emtricitabine and Tenofovir Alafenamide
Brand: DESCOVY
$71.41Lowest NADAC
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06
Emtricitabine, Rilpivirine Hydrochloride, and Tenofovir Alafenamide
Brand: ODEFSEY
$130.35Lowest NADAC
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Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (18 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.