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Live data · NADAC + Part D CY24 · reviewed daily

Emtricitabine, Rilpivirine Hydrochloride, and Tenofovir Disoproxil (COMPLERA)

Emtricitabine, Rilpivirine Hydrochloride, and Tenofovir Disoproxil blocks HIV replication by inhibiting reverse transcriptase.

First FDA approval2011-08-10
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$130.52/unit
1 NDCs benchmarked, lowest of all strengths.
Average NADAC
$130.52
Across all dosage forms in distribution.
Highest NADAC
$130.52
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema9 entries indexed · 4 visible
What is Emtricitabine, Rilpivirine Hydrochloride, and Tenofovir Disoproxil used for?

Emtricitabine, Rilpivirine Hydrochloride, and Tenofovir Disoproxil blocks HIV replication by inhibiting reverse transcriptase.

Is there a generic for Emtricitabine, Rilpivirine Hydrochloride, and Tenofovir Disoproxil?

No. Emtricitabine, Rilpivirine Hydrochloride, and Tenofovir Disoproxil is brand-only with no generic equivalents currently in market.

How much does my plan pay for Emtricitabine, Rilpivirine Hydrochloride, and Tenofovir Disoproxil?

Across 329 Part D plans, Emtricitabine, Rilpivirine Hydrochloride, and Tenofovir Disoproxil averages $130.52/unit (NADAC). Lowest available: $130.52/unit. Highest in distribution: $130.52/unit.

Is Emtricitabine, Rilpivirine Hydrochloride, and Tenofovir Disoproxil on the FDA shortage list?

No. Emtricitabine, Rilpivirine Hydrochloride, and Tenofovir Disoproxil is not currently on the FDA Drug Shortage Database.

5 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor6 alternatives in D1
01
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02
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04
Emtricitabine and Tdf
Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor
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05
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06
Emtricitabine and Tenofovir Disoproxil
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Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book · NADAC unit costs: CMS NADAC weekly file (1 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.