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Live data · NADAC + Part D CY24 · reviewed daily

Enzalutamide (Xtandi)

XTANDI ® is indicated for the treatment of patients with: • castration-resistant prostate cancer (CRPC) • metastatic castration-sensitive prostate cancer (mCSPC) • non‑metastatic castration‑sensiti....

First FDA approval2012-08-31
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$5.84B in CY2024 Part D spend433K claims · 75K beneficiaries · 329 plans surveyed

Lowest NADAC
/unit
0 NDCs benchmarked, lowest of all strengths.
Average NADAC
Across all dosage forms in distribution.
Highest NADAC
Range is tight.
Plans with PA
981 / 329
Substantial PA friction across plans.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Enzalutamide used for?

XTANDI ® is indicated for the treatment of patients with: • castration-resistant prostate cancer (CRPC) • metastatic castration-sensitive prostate cancer (mCSPC) • non‑metastatic castration‑sensiti....

Is there a generic for Enzalutamide?

No. Enzalutamide is brand-only with no generic equivalents currently in market.

How much does my plan pay for Enzalutamide?

NADAC pricing data not currently available for this drug.

Is Enzalutamide on the FDA shortage list?

No. Enzalutamide is not currently on the FDA Drug Shortage Database.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Androgen Receptor Inhibitor4 alternatives in D1
01
Bicalutamide
Brand: CASODEX
$0.403Lowest NADAC
6Generic mfrs
$10.9MCY24 Part D spend
Compare →
02
Clascoterone
Brand: Winlevi
$9.99Lowest NADAC
0Generic mfrs
$1.7MCY24 Part D spend
Compare →
03
Flutamide
Brand: Eulexin
Lowest NADAC
1Generic mfrs
$216,500CY24 Part D spend
Compare →
04
Nilutamide
Brand: Nilandron
Lowest NADAC
1Generic mfrs
$1.4MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (3 approvals on file) · NADAC unit costs: CMS NADAC weekly file · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.