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Live data · NADAC + Part D CY24 · reviewed daily

Epcoritamab-Bysp (EPKINLY)

Bispecific CD20-directed CD3 T Cell Engager class · 0 generic manufacturers · 0 ANDAs filed at FDA.

First FDA approval2023-05-19
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$1.8M in CY2024 Part D spend65 claims · — beneficiaries · 329 plans surveyed

Lowest NADAC
/unit
0 NDCs benchmarked, lowest of all strengths.
Average NADAC
Across all dosage forms in distribution.
Highest NADAC
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema10 entries indexed · 4 visible
What is Epcoritamab-Bysp used for?

Epcoritamab-Bysp is a Bispecific CD20-directed CD3 T Cell Engager medication tracked in Medicare Part D.

Is there a generic for Epcoritamab-Bysp?

No. Epcoritamab-Bysp is brand-only with no generic equivalents currently in market.

How much does my plan pay for Epcoritamab-Bysp?

NADAC pricing data not currently available for this drug.

Is Epcoritamab-Bysp on the FDA shortage list?

No. Epcoritamab-Bysp is not currently on the FDA Drug Shortage Database.

6 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Bispecific CD20-directed CD3 T Cell Engager1 alternative in D1
01
Glofitamab
Brand: Columvi
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book · NADAC unit costs: CMS NADAC weekly file · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.