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Live data · NADAC + Part D CY24 · reviewed daily

Esmolol (BREVIBLOC)

Esmolol slows heart rate and lowers blood pressure, used for hypertension, heart failure, and arrhythmias.

First FDA approval1986-12-31
Generic availableYes · 8 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
/unit
0 NDCs benchmarked, lowest of all strengths.
Average NADAC
Across all dosage forms in distribution.
Highest NADAC
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema10 entries indexed · 4 visible
What is Esmolol used for?

Esmolol slows heart rate and lowers blood pressure, used for hypertension, heart failure, and arrhythmias.

Is there a generic for Esmolol?

Yes. 14 ANDAs filed at FDA, 8 generic manufacturers currently shipping.

How much does my plan pay for Esmolol?

NADAC pricing data not currently available for this drug.

Is Esmolol on the FDA shortage list?

No. Esmolol is not currently on the FDA Drug Shortage Database.

6 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

beta-Adrenergic Blocker6 alternatives in D1
01
Atenolol
Brand: TENORMIN
$0.022Lowest NADAC
9Generic mfrs
$77.9MCY24 Part D spend
Compare →
02
Betaxolol
Brand: Betoptic S
$0.603Lowest NADAC
4Generic mfrs
$8.5MCY24 Part D spend
Compare →
03
Esmolol Hydrochloride In Sodium
Brand: Esmolol Hydrochloride
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
04
Labetalol
Brand: Labetalol Hydrochloride
$0.079Lowest NADAC
19Generic mfrs
$45.5MCY24 Part D spend
Compare →
05
Nadolol
beta-Adrenergic Blocker
$0.193Lowest NADAC
10Generic mfrs
$21.2MCY24 Part D spend
Compare →
06
Nebibolol
Brand: NEBIVOLOL
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.