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Live data · NADAC + Part D CY24 · reviewed daily

Etoposide (Avopef)

Topoisomerase Inhibitor class · 5 generic manufacturers · 5 ANDAs filed at FDA.

First FDA approval1996-05-01
Generic availableYes · 5 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$36,955 in CY2024 Part D spend608 claims · 208 beneficiaries · 329 plans surveyed

Lowest NADAC
/unit
0 NDCs benchmarked, lowest of all strengths.
Average NADAC
Across all dosage forms in distribution.
Highest NADAC
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Etoposide used for?

Etoposide is a Topoisomerase Inhibitor medication tracked in Medicare Part D.

Is there a generic for Etoposide?

Yes. 5 ANDAs filed at FDA, 5 generic manufacturers currently shipping.

How much does my plan pay for Etoposide?

NADAC pricing data not currently available for this drug.

Is Etoposide on the FDA shortage list?

No. Etoposide is not currently on the FDA Drug Shortage Database.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Topoisomerase Inhibitor2 alternatives in D1
01
Irinotecan
Brand: Camptosar
Lowest NADAC
15Generic mfrs
$715,899CY24 Part D spend
Compare →
02
Topotecan
Brand: HYCAMTIN
Lowest NADAC
7Generic mfrs
$27,966CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (8 approvals on file) · NADAC unit costs: CMS NADAC weekly file · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.