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Live data · NADAC + Part D CY24 · reviewed daily

Ezetimibe and Simvastatin (VYTORIN)

Ezetimibe and Simvastatin lowers LDL cholesterol and triglycerides to reduce cardiovascular risk.

First FDA approval2017-04-26
Generic availableYes · 4 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$0.318/unit
20 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.333
Across all dosage forms in distribution.
Highest NADAC
$0.346
Range is tight.
Plans with PA
3 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema10 entries indexed · 4 visible
What is Ezetimibe and Simvastatin used for?

Ezetimibe and Simvastatin lowers LDL cholesterol and triglycerides to reduce cardiovascular risk.

Is there a generic for Ezetimibe and Simvastatin?

Yes. 16 ANDAs filed at FDA, 4 generic manufacturers currently shipping.

How much does my plan pay for Ezetimibe and Simvastatin?

Across 329 Part D plans, Ezetimibe and Simvastatin averages $0.333/unit (NADAC). Lowest available: $0.318/unit. Highest in distribution: $0.346/unit.

Is Ezetimibe and Simvastatin on the FDA shortage list?

No. Ezetimibe and Simvastatin is not currently on the FDA Drug Shortage Database.

6 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

HMG-CoA Reductase Inhibitor5 alternatives in D1
01
Atorvastatin
Brand: Lipitor
$0.025Lowest NADAC
22Generic mfrs
$1.20BCY24 Part D spend
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02
Lovastatin
HMG-CoA Reductase Inhibitor
$0.038Lowest NADAC
7Generic mfrs
$38.5MCY24 Part D spend
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03
Pitavastatin
Brand: Livalo
$1.16Lowest NADAC
8Generic mfrs
$182.6MCY24 Part D spend
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04
Rosuvastatin
Brand: Crestor
$0.035Lowest NADAC
18Generic mfrs
$716.1MCY24 Part D spend
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05
Simvastatin
Brand: ZOCOR
$0.028Lowest NADAC
11Generic mfrs
$190.2MCY24 Part D spend
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Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (20 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.