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Live data · NADAC + Part D CY24 · reviewed daily

Fam-Trastuzumab Deruxtecan-Nxki (Enhertu)

First FDA approval2019-12-20
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
—/unit
0 NDCs benchmarked, lowest of all strengths.
Average NADAC
—
Across all dosage forms in distribution.
Highest NADAC
—
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema7 entries indexed · 4 visible
What is Fam-Trastuzumab Deruxtecan-Nxki used for?

Fam-Trastuzumab Deruxtecan-Nxki is a this drug class medication tracked in Medicare Part D.

Sources: CMS Part D Spending CY24 · CMS NADAC weekly · FDA Orange Book
Is there a generic for Fam-Trastuzumab Deruxtecan-Nxki?

No. Fam-Trastuzumab Deruxtecan-Nxki is brand-only with no generic equivalents currently in market.

Sources: CMS Part D Spending CY24 · CMS NADAC weekly · FDA Orange Book
How much does my plan pay for Fam-Trastuzumab Deruxtecan-Nxki?

NADAC pricing data not currently available for this drug.

Sources: CMS Part D Spending CY24 · CMS NADAC weekly · FDA Orange Book
Is Fam-Trastuzumab Deruxtecan-Nxki on the FDA shortage list?

No. Fam-Trastuzumab Deruxtecan-Nxki is not currently on the FDA Drug Shortage Database.

Sources: CMS Part D Spending CY24 · CMS NADAC weekly · FDA Orange Book

3 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Related questions.

Q&A librarySourced · reviewed quarterly
pricingWhat is NADAC?pricingIs NADAC the same as my PBM cost?pricingWhat is spread pricing?pricingWhat is a NADAC pass-through PBM contract?pricingWhat's the difference between AWP, MAC, and NADAC?pricingWhat is a dispensing fee in a PBM contract?
Browse all canonical questions →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book · NADAC unit costs: CMS NADAC weekly file · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.