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Live data · NADAC + Part D CY24 · reviewed daily

Fondaparinux (Arixtra)

Fondaparinux prevents blood clots by inhibiting factor Xa, prescribed for atrial fibrillation and venous thromboembolism.

First FDA approval2011-07-14
Generic availableYes · 4 mfrs
Shortage statusDiscontinued
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$21.9M in CY2024 Part D spend20K claims · 5K beneficiaries · 329 plans surveyed

Lowest NADAC
$12.77/unit
20 NDCs benchmarked, lowest of all strengths.
Average NADAC
$34.71
Across all dosage forms in distribution.
Highest NADAC
$55.31
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema12 entries indexed · 4 visible
What is Fondaparinux used for?

Fondaparinux prevents blood clots by inhibiting factor Xa, prescribed for atrial fibrillation and venous thromboembolism.

Is there a generic for Fondaparinux?

Yes. 16 ANDAs filed at FDA, 4 generic manufacturers currently shipping.

How much does my plan pay for Fondaparinux?

Across 329 Part D plans, Fondaparinux averages $34.71/unit (NADAC). Lowest available: $12.77/unit. Highest in distribution: $55.31/unit.

Is Fondaparinux on the FDA shortage list?

Fondaparinux has been discontinued by its manufacturer(s).

8 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Factor Xa Inhibitor3 alternatives in D1
01
Apixaban
Brand: ELIQUIS
$5.51Lowest NADAC
2Generic mfrs
$32.24BCY24 Part D spend
Compare →
02
Rivaroxaban
Brand: XARELTO
$0.979Lowest NADAC
17Generic mfrs
$9.48BCY24 Part D spend
Compare →
03
Rivaroxaban Granule
Factor Xa Inhibitor
$1.96Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (20 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.