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Live data · NADAC + Part D CY24 · reviewed daily

Glipizide and Metformin

Glipizide and Metformin stimulates insulin release from the pancreas to lower blood sugar.

First FDA approval2005-10-28
Generic availableYes · 4 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$0.219/unit
12 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.236
Across all dosage forms in distribution.
Highest NADAC
$0.246
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema8 entries indexed · 4 visible
What is Glipizide and Metformin used for?

Glipizide and Metformin stimulates insulin release from the pancreas to lower blood sugar.

Is there a generic for Glipizide and Metformin?

Yes. 12 ANDAs filed at FDA, 4 generic manufacturers currently shipping.

How much does my plan pay for Glipizide and Metformin?

Across 329 Part D plans, Glipizide and Metformin averages $0.236/unit (NADAC). Lowest available: $0.219/unit. Highest in distribution: $0.246/unit.

Is Glipizide and Metformin on the FDA shortage list?

No. Glipizide and Metformin is not currently on the FDA Drug Shortage Database.

4 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Sulfonylurea6 alternatives in D1
01
Glimepiride
Sulfonylurea
$0.024Lowest NADAC
8Generic mfrs
$62.0MCY24 Part D spend
Compare →
02
Glipizide
Brand: Glucotrol
$0.036Lowest NADAC
11Generic mfrs
$138.2MCY24 Part D spend
Compare →
03
Glipizide-Tablets
Brand: GLIPIZIDE
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
04
Glyburide
Sulfonylurea
$0.058Lowest NADAC
7Generic mfrs
$4.5MCY24 Part D spend
Compare →
05
Glyburide and Metformin
Sulfonylurea
$0.192Lowest NADAC
5Generic mfrs
CY24 Part D spend
Compare →
06
Glyburide-Metformin
Sulfonylurea
$0.192Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (12 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.