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Live data · NADAC + Part D CY24 · reviewed daily

Glyburide

Glyburide stimulates insulin release from the pancreas to lower blood sugar.

First FDA approval1984-05-01
Generic availableYes · 7 mfrs
Shortage statusDiscontinued
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$4.5M in CY2024 Part D spend291K claims · 103K beneficiaries · 329 plans surveyed

Lowest NADAC
$0.058/unit
20 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.064
Across all dosage forms in distribution.
Highest NADAC
$0.080
Range is tight.
Plans with PA
219 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema9 entries indexed · 4 visible
What is Glyburide used for?

Glyburide stimulates insulin release from the pancreas to lower blood sugar.

Is there a generic for Glyburide?

Yes. 25 ANDAs filed at FDA, 7 generic manufacturers currently shipping.

How much does my plan pay for Glyburide?

Across 329 Part D plans, Glyburide averages $0.064/unit (NADAC). Lowest available: $0.058/unit. Highest in distribution: $0.080/unit.

Is Glyburide on the FDA shortage list?

Glyburide has been discontinued by its manufacturer(s).

5 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Sulfonylurea6 alternatives in D1
01
Glimepiride
Sulfonylurea
$0.024Lowest NADAC
8Generic mfrs
$62.0MCY24 Part D spend
Compare →
02
Glipizide
Brand: Glucotrol
$0.036Lowest NADAC
11Generic mfrs
$138.2MCY24 Part D spend
Compare →
03
Glipizide and Metformin
Sulfonylurea
$0.219Lowest NADAC
4Generic mfrs
CY24 Part D spend
Compare →
04
Glipizide-Tablets
Brand: GLIPIZIDE
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
05
Glyburide and Metformin
Sulfonylurea
$0.192Lowest NADAC
5Generic mfrs
CY24 Part D spend
Compare →
06
Glyburide-Metformin
Sulfonylurea
$0.192Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (20 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.