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Live data · NADAC + Part D CY24 · reviewed daily

Granisetron (Granisetron)

Serotonin-3 Receptor Antagonist class · 13 generic manufacturers · 32 ANDAs filed at FDA.

First FDA approval2009-06-22
Generic availableYes · 13 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$11.1M in CY2024 Part D spend18K claims · 7K beneficiaries · 329 plans surveyed

Lowest NADAC
$1.10/unit
8 NDCs benchmarked, lowest of all strengths.
Average NADAC
$84.55
Across all dosage forms in distribution.
Highest NADAC
$668.76
Wide spread — brand-strength NDCs still in market.
Plans with PA
239 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema10 entries indexed · 4 visible
What is Granisetron used for?

Granisetron is a Serotonin-3 Receptor Antagonist medication tracked in Medicare Part D.

Is there a generic for Granisetron?

Yes. 32 ANDAs filed at FDA, 13 generic manufacturers currently shipping.

How much does my plan pay for Granisetron?

Across 329 Part D plans, Granisetron averages $84.55/unit (NADAC). Lowest available: $1.10/unit. Highest in distribution: $668.76/unit.

Is Granisetron on the FDA shortage list?

No. Granisetron is not currently on the FDA Drug Shortage Database.

6 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Serotonin-3 Receptor Antagonist5 alternatives in D1
01
Alosetron
Brand: LOTRONEX
$2.22Lowest NADAC
4Generic mfrs
$14.6MCY24 Part D spend
Compare →
02
Fosnetupitant and Palonosetron
Brand: AKYNZEO
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
03
Netupitant and Palonosetron
Brand: AKYNZEO
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
04
Ondansetron
Brand: ONDANSETRON
$0.064Lowest NADAC
19Generic mfrs
$218.9MCY24 Part D spend
Compare →
05
Palonosetron
Brand: Palonosetron
Lowest NADAC
13Generic mfrs
$409,092CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (8 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.