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Live data · NADAC + Part D CY24 · reviewed daily

Guselkumab (TREMFYA)

TREMFYA is an interleukin-23 antagonist indicated for the treatment of: adults and pediatric patients 6 years of age and older who also weigh at least 40 kg with moderate-to-severe plaque psoriasis....

First FDA approval2017-07-13
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$1.13B in CY2024 Part D spend82K claims · 26K beneficiaries · 329 plans surveyed

Lowest NADAC
$7349.67/unit
3 NDCs benchmarked, lowest of all strengths.
Average NADAC
$12295.24
Across all dosage forms in distribution.
Highest NADAC
$14769.74
Range is tight.
Plans with PA
1340 / 329
Substantial PA friction across plans.

Questions a plan sponsor actually asks.

FAQPage schema10 entries indexed · 4 visible
What is Guselkumab used for?

TREMFYA is an interleukin-23 antagonist indicated for the treatment of: adults and pediatric patients 6 years of age and older who also weigh at least 40 kg with moderate-to-severe plaque psoriasis....

Is there a generic for Guselkumab?

No. Guselkumab is brand-only with no generic equivalents currently in market.

How much does my plan pay for Guselkumab?

Across 329 Part D plans, Guselkumab averages $12295.24/unit (NADAC). Lowest available: $7349.67/unit. Highest in distribution: $14769.74/unit.

Is Guselkumab on the FDA shortage list?

No. Guselkumab is not currently on the FDA Drug Shortage Database.

6 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Interleukin-23 Antagonist3 alternatives in D1
01
Mirikizumab-Mrkz
Brand: Omvoh
Lowest NADAC
0Generic mfrs
$11.0MCY24 Part D spend
Compare →
02
Risankizumab-Rzaa
Brand: Skyrizi
$9679.49Lowest NADAC
0Generic mfrs
$4.58BCY24 Part D spend
Compare →
03
Tildrakizumab-Asmn
Brand: ILUMYA
Lowest NADAC
0Generic mfrs
$57.1MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book · NADAC unit costs: CMS NADAC weekly file (3 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.