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Live data · NADAC + Part D CY24 · reviewed daily

Hydralazine and Isosorbide Dinitrate (BiDil)

Hydralazine and Isosorbide Dinitrate dilates blood vessels to relieve chest pain from angina.

First FDA approval2012-12-05
Generic availableYes · 2 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$0.778/unit
2 NDCs benchmarked, lowest of all strengths.
Average NADAC
$2.56
Across all dosage forms in distribution.
Highest NADAC
$4.35
Wide spread — brand-strength NDCs still in market.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema12 entries indexed · 4 visible
What is Hydralazine and Isosorbide Dinitrate used for?

Hydralazine and Isosorbide Dinitrate dilates blood vessels to relieve chest pain from angina.

Is there a generic for Hydralazine and Isosorbide Dinitrate?

Yes. 2 ANDAs filed at FDA, 2 generic manufacturers currently shipping.

How much does my plan pay for Hydralazine and Isosorbide Dinitrate?

Across 329 Part D plans, Hydralazine and Isosorbide Dinitrate averages $2.56/unit (NADAC). Lowest available: $0.778/unit. Highest in distribution: $4.35/unit.

Is Hydralazine and Isosorbide Dinitrate on the FDA shortage list?

No. Hydralazine and Isosorbide Dinitrate is not currently on the FDA Drug Shortage Database.

8 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Nitrate Vasodilator6 alternatives in D1
01
Isosorbide Dinitrate
Brand: Isosorbide
$0.071Lowest NADAC
5Generic mfrs
$41.5MCY24 Part D spend
Compare →
02
Isosorbide Dinitrate and Hydralazine
Nitrate Vasodilator
$0.778Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
03
Isosorbide Mononitrate
Nitrate Vasodilator
$0.071Lowest NADAC
8Generic mfrs
$95.1MCY24 Part D spend
Compare →
04
Nitroglycerin
Brand: NITRO-BID
$0.073Lowest NADAC
16Generic mfrs
$69.4MCY24 Part D spend
Compare →
05
Nitroglycerin Lingual
Nitrate Vasodilator
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
06
Nitroglycerin Tablet
Brand: NITROSTAT
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (3 approvals on file) · NADAC unit costs: CMS NADAC weekly file (2 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.