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Live data · NADAC + Part D CY24 · reviewed daily

Ibuprofen and Famotidine

Histamine-2 Receptor Antagonist class · 4 generic manufacturers · 4 ANDAs filed at FDA.

First FDA approval2021-08-04
Generic availableYes · 4 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$0.702/unit
4 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.702
Across all dosage forms in distribution.
Highest NADAC
$0.702
Range is tight.
Plans with PA
6 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema8 entries indexed · 4 visible
What is Ibuprofen and Famotidine used for?

Ibuprofen and Famotidine is a Histamine-2 Receptor Antagonist medication tracked in Medicare Part D.

Is there a generic for Ibuprofen and Famotidine?

Yes. 4 ANDAs filed at FDA, 4 generic manufacturers currently shipping.

How much does my plan pay for Ibuprofen and Famotidine?

Across 329 Part D plans, Ibuprofen and Famotidine averages $0.702/unit (NADAC). Lowest available: $0.702/unit. Highest in distribution: $0.702/unit.

Is Ibuprofen and Famotidine on the FDA shortage list?

No. Ibuprofen and Famotidine is not currently on the FDA Drug Shortage Database.

4 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Histamine-2 Receptor Antagonist5 alternatives in D1
01
Cimetidine
Histamine-2 Receptor Antagonist
$0.205Lowest NADAC
7Generic mfrs
$9.0MCY24 Part D spend
Compare →
02
Famotidine
Brand: Pepcid
$0.030Lowest NADAC
34Generic mfrs
$257.1MCY24 Part D spend
Compare →
03
Ibuprofen Famotidine
Histamine-2 Receptor Antagonist
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
04
Nizatidine
Histamine-2 Receptor Antagonist
$0.799Lowest NADAC
3Generic mfrs
$670,367CY24 Part D spend
Compare →
05
Ranitidine
Histamine-2 Receptor Antagonist
Lowest NADAC
4Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (4 approvals on file) · NADAC unit costs: CMS NADAC weekly file (4 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.