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Isosorbide Mononitrate

Isosorbide Mononitrate dilates blood vessels to relieve chest pain from angina.

First FDA approval1993-06-30
Generic availableYes · 8 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$95.1M in CY2024 Part D spend7.2M claims · 2.2M beneficiaries · 329 plans surveyed

Lowest NADAC
$0.071/unit
20 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.082
Across all dosage forms in distribution.
Highest NADAC
$0.096
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema9 entries indexed · 4 visible
What is Isosorbide Mononitrate used for?

Isosorbide Mononitrate dilates blood vessels to relieve chest pain from angina.

Is there a generic for Isosorbide Mononitrate?

Yes. 23 ANDAs filed at FDA, 8 generic manufacturers currently shipping.

How much does my plan pay for Isosorbide Mononitrate?

Across 329 Part D plans, Isosorbide Mononitrate averages $0.082/unit (NADAC). Lowest available: $0.071/unit. Highest in distribution: $0.096/unit.

Is Isosorbide Mononitrate on the FDA shortage list?

No. Isosorbide Mononitrate is not currently on the FDA Drug Shortage Database.

5 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Nitrate Vasodilator6 alternatives in D1
01
Hydralazine and Isosorbide Dinitrate
Brand: BiDil
$0.778Lowest NADAC
2Generic mfrs
CY24 Part D spend
Compare →
02
Isosorbide Dinitrate
Brand: Isosorbide
$0.071Lowest NADAC
5Generic mfrs
$41.5MCY24 Part D spend
Compare →
03
Isosorbide Dinitrate and Hydralazine
Nitrate Vasodilator
$0.778Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
04
Nitroglycerin
Brand: NITRO-BID
$0.073Lowest NADAC
16Generic mfrs
$69.4MCY24 Part D spend
Compare →
05
Nitroglycerin Lingual
Nitrate Vasodilator
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
06
Nitroglycerin Tablet
Brand: NITROSTAT
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (20 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.