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Live data · NADAC + Part D CY24 · reviewed daily

Itraconazole (SPORANOX)

Itraconazole treats fungal infections by inhibiting ergosterol synthesis in fungal cell membranes.

First FDA approval1992-09-11
Generic availableYes · 8 mfrs
Shortage statusDiscontinued
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$11.6M in CY2024 Part D spend58K claims · 26K beneficiaries · 329 plans surveyed

Lowest NADAC
$0.838/unit
16 NDCs benchmarked, lowest of all strengths.
Average NADAC
$4.32
Across all dosage forms in distribution.
Highest NADAC
$28.36
Wide spread — brand-strength NDCs still in market.
Plans with PA
69 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema12 entries indexed · 4 visible
What is Itraconazole used for?

Itraconazole treats fungal infections by inhibiting ergosterol synthesis in fungal cell membranes.

Is there a generic for Itraconazole?

Yes. 9 ANDAs filed at FDA, 8 generic manufacturers currently shipping.

How much does my plan pay for Itraconazole?

Across 329 Part D plans, Itraconazole averages $4.32/unit (NADAC). Lowest available: $0.838/unit. Highest in distribution: $28.36/unit.

Is Itraconazole on the FDA shortage list?

Itraconazole has been discontinued by its manufacturer(s).

8 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Azole Antifungal6 alternatives in D1
01
Clotrimazole
Brand: CLOTIC (clotrimazole) otic solution
$0.138Lowest NADAC
10Generic mfrs
$33.8MCY24 Part D spend
Compare →
02
Clotrimazole Topical
Brand: Clotrimazole
$0.517Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
03
Clotrimazole Topical Solution Usp,
Azole Antifungal
$0.517Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
04
Clotrimazole and Betameth
Azole Antifungal
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
05
Clotrimazole and Betamethasone Dipropionate
Azole Antifungal
$0.181Lowest NADAC
4Generic mfrs
CY24 Part D spend
Compare →
06
Efinaconazole
Brand: JUBLIA
Lowest NADAC
3Generic mfrs
$179.1MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (16 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.