A BuiltForAI Property
Live data · NADAC + Part D CY24 · reviewed daily

Lactulose (Constulose)

Lactulose draws water into the bowel to relieve constipation.

First FDA approval1966-07-30
Generic availableYes · 12 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$116.6M in CY2024 Part D spend3.0M claims · 1.2M beneficiaries · 329 plans surveyed

Lowest NADAC
$0.013/unit
20 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.020
Across all dosage forms in distribution.
Highest NADAC
$0.025
Range is tight.
Plans with PA
28 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Lactulose used for?

Lactulose draws water into the bowel to relieve constipation.

Is there a generic for Lactulose?

Yes. 16 ANDAs filed at FDA, 12 generic manufacturers currently shipping.

How much does my plan pay for Lactulose?

Across 329 Part D plans, Lactulose averages $0.020/unit (NADAC). Lowest available: $0.013/unit. Highest in distribution: $0.025/unit.

Is Lactulose on the FDA shortage list?

No. Lactulose is not currently on the FDA Drug Shortage Database.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Osmotic Laxative6 alternatives in D1
01
Lactulose Solution Usp,
Brand: Lactulose Solution
$0.013Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
02
Polyethylene Glycol 3350 and Electrolytes - Unflavored
Osmotic Laxative
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
03
Polyethylene Glycol 3350 and Electrolytes With Lemon Flavor
Osmotic Laxative
$0.005Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
04
Polyethylene Glycol 3350 and Electrolytes With Orange Flavor
Brand: Polyethylene Glycol 3350 and electrolyteswith Orange Flavor
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
05
Polyethylene Glycol 3350, Sodium Chloride, Sodium Bicarbonate and Potassium Chloride - Unflavored
Osmotic Laxative
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
06
Polyethylene Glycol 3350, Sodium Chloride, Sodium Bicarbonate and Potassium Chloride With Lemon Flavor
Osmotic Laxative
$0.006Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (20 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.