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Live data · NADAC + Part D CY24 · reviewed daily

Linagliptin and Metformin (Jentadueto)

Dipeptidyl Peptidase 4 Inhibitor class · 4 generic manufacturers · 12 ANDAs filed at FDA.

First FDA approval2012-02-13
Generic availableYes · 4 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$8.44/unit
10 NDCs benchmarked, lowest of all strengths.
Average NADAC
$10.15
Across all dosage forms in distribution.
Highest NADAC
$16.94
Range is tight.
Plans with PA
4 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Linagliptin and Metformin used for?

Linagliptin and Metformin is a Dipeptidyl Peptidase 4 Inhibitor medication tracked in Medicare Part D.

Is there a generic for Linagliptin and Metformin?

Yes. 12 ANDAs filed at FDA, 4 generic manufacturers currently shipping.

How much does my plan pay for Linagliptin and Metformin?

Across 329 Part D plans, Linagliptin and Metformin averages $10.15/unit (NADAC). Lowest available: $8.44/unit. Highest in distribution: $16.94/unit.

Is Linagliptin and Metformin on the FDA shortage list?

No. Linagliptin and Metformin is not currently on the FDA Drug Shortage Database.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Dipeptidyl Peptidase 4 Inhibitor4 alternatives in D1
01
Linagliptin
Brand: Tradjenta
$16.80Lowest NADAC
7Generic mfrs
$1.64BCY24 Part D spend
Compare →
02
Sitagliptin
Brand: JANUVIA
$10.04Lowest NADAC
3Generic mfrs
$4.88BCY24 Part D spend
Compare →
03
Sitagliptin Hydrochloride Oral
Brand: BRYNOVIN
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
04
Sitagliptin and Metformin
Brand: JANUMET
$5.03Lowest NADAC
1Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (10 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.