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Live data · NADAC + Part D CY24 · reviewed daily

Lopinavir and Ritonavir (Kaletra)

Cytochrome P450 3A Inhibitor class · 5 generic manufacturers · 10 ANDAs filed at FDA.

First FDA approval2010-06-18
Generic availableYes · 5 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$4.70/unit
2 NDCs benchmarked, lowest of all strengths.
Average NADAC
$4.70
Across all dosage forms in distribution.
Highest NADAC
$4.70
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema10 entries indexed · 4 visible
What is Lopinavir and Ritonavir used for?

Lopinavir and Ritonavir is a Cytochrome P450 3A Inhibitor medication tracked in Medicare Part D.

Is there a generic for Lopinavir and Ritonavir?

Yes. 10 ANDAs filed at FDA, 5 generic manufacturers currently shipping.

How much does my plan pay for Lopinavir and Ritonavir?

Across 329 Part D plans, Lopinavir and Ritonavir averages $4.70/unit (NADAC). Lowest available: $4.70/unit. Highest in distribution: $4.70/unit.

Is Lopinavir and Ritonavir on the FDA shortage list?

No. Lopinavir and Ritonavir is not currently on the FDA Drug Shortage Database.

6 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Cytochrome P450 3A Inhibitor6 alternatives in D1
01
Atazanavir and Cobicistat
Brand: EVOTAZ
$51.98Lowest NADAC
0Generic mfrs
CY24 Part D spend
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02
Cobicistat
Brand: Tybost
Lowest NADAC
0Generic mfrs
$391,226CY24 Part D spend
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03
Darunavir Ethanolate and Cobicistat
Brand: PREZCOBIX
$79.99Lowest NADAC
0Generic mfrs
CY24 Part D spend
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04
Darunavir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide
Brand: Symtuza
$152.95Lowest NADAC
0Generic mfrs
CY24 Part D spend
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05
Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide
Brand: Genvoya
$143.35Lowest NADAC
0Generic mfrs
CY24 Part D spend
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06
Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Disoproxil
Brand: Stribild
$150.41Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (2 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.